Research Impact: This narrative review explores nutritional strategies to improve sarcopenia outcomes in older adults. Sarcopenia, a condition characterized by muscle loss, decreased strength, and reduced physical performance, is associated with aging and chronic illnesses, significantly impacting independence and quality of life. The review highlights the role of nutritional interventions alongside exercise in mitigating sarcopenia’s effects. Key findings emphasize the importance of adequate protein intake to counteract age-related anabolic resistance. Recommendations include consuming 1.0–1.5 g of protein per kg of body weight daily, distributed evenly across meals. Whey protein is identified as the most effective supplement for enhancing muscle protein synthesis (MPS), especially when combined with resistance training. Alternatives like fish protein hydrolysates and plant-based proteins show potential but require higher doses or strategic combinations to match whey protein’s benefits. Supplements such as leucine, essential amino acids (EAAs), and creatine demonstrate promise in boosting MPS and improving muscle mass and function. Omega-3 fatty acids, known for their anti-inflammatory properties, also show benefits for muscle strength and metabolism. The review underscores the need for tailored nutritional strategies, highlighting the interplay between diet and physical activity in managing sarcopenia. Future research should focus on optimising dosages, timing, and combinations of supplements to maximise outcomes for older adults.
Goes-Santos, B. R., Carson, B. P., da Fonseca, G. W. P., & von Haehling, S. (2024). Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review. Pharmacology research & perspectives, 12(5), e70019. https://doi.org/10.1002/prp2.70019
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